Daniel Ojeda Juarez, a postdoctoral researcher at UC San Diego, explores the link between protein aggregation and cognitive ...

The virus causing the ongoing COVID-19 pandemic, SARS-CoV-2, has spread far more quickly than any other coronavirus in recorded history. Why is it so contagious? One possibility is that its spike ...

Researchers have synthesized the first artificial human prion, a dramatic development in efforts to combat a devastating form of brain disease that has so far eluded treatment and a cure. Case Western ...

The misfolding of proteins and their subsequent deposition as amyloid in peripheral nerves lead to sensory and autonomic neuropathy A new hereditary form of neuropathy, prion protein (PrP) systemic ...

Abnormal prion proteins are little understood disease agents involved in causing horrific brain-wasting diseases such as Creutzfeldt-Jacob disease in people, mad cow disease in cattle and chronic ...

CLEVELAND - A new sporadic prion protein disease has been discovered. Variably protease-sensitive prionopathy (VPSPr), as it has been named, is the second type of complete sporadic disease to be ...

Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease in cattle, and chronic wasting disease in elk and deer. The infectious, misfolded protein ...

Close-up on three ropes and marine knots isolated on white background. Each is photographed separately. Prion diseases are rare but deadly neurodegenerative brain diseases that result from misfolding ...

New research from David Westaway, PhD, of the University of Alberta and Jiri Safar, MD, Case Western Reserve University School of Medicine has uncovered a quality control mechanism in brain cells that ...

Prion diseases are progressive nervous system diseases which always have a fatal outcome. They are transmissible and affect many mammals. They are also called transmissible spongiform encephalopathies ...