Single-cell sequencing methods are revolutionizing our ability to characterize tissues across developmental stages, diseases and individuals, and following large-scale genetic perturbations 1,2.

Existing annotation paradigms rely on controlled vocabularies, where each data instance is classified into one term from a predefined set of controlled vocabularies. This paradigm restricts the ...

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like ...

For decades, reading proteins has remained an analog challenge in a digital world. Researchers at Stanford University have developed a “reverse translation” method that converts protein sequences into ...

The German Institute for Quality and Efficiency in Health Care (IQWiG) completed the update of its methods paper to Version 7.0 and published the currently valid version of its "General Methods" on ...