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Only inject Repatha (evolocumab) on its scheduled day. Do not inject a dose in advance. The timing of your Repatha dose on an injection day isn’t important, so you can adjust it as needed on that day.

Repatha is the Only PCSK9 Inhibitor to Significantly Reduce the Risk of First CV Events in High-Risk Primary Prevention VESALIUS-CV Subgroup Findings Reinforce Benefit of Earlier Initiation of Repatha ...

Repatha was first approved in 2015 and has since been used by more than 8 million patients globally. 5,6 In August 2025, the U.S. Food and Drug Administration broadened the approved use of Repatha to ...