A new study reveals that malignant transformation of intestinal stem cells (ISCs) and their supportive microenvironment ...

Drosophila melanogaster has long served as a powerful model for dissecting the principles of tissue homeostasis and regeneration. Within the adult midgut, intestinal stem cells (ISCs) perform the ...

Image Caption: The signaling pathways involved in the intestinal stem cell niche and cell fate determination. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and ...

The interplay between the circadian clock, intestinal stem cell niche, and epithelial cell fate is shaping our understanding of how gut homeostasis and cellular regeneration are regulated. Recent ...

3 Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. 4 Molecular Immunology Research Center and ...

A new study reveals that age-related changes in the gut microbiota directly impair intestinal stem cell (ISC) function and that restoring a youthful microbial environment can reverse this decline.

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

Stem cells in most organisms typically take cues from adjacent cells. But new research from the Stowers Institute for Medical Research has found that stem cells in the freshwater planarian Schmidtea ...