Mass spec is poised to fulfill its potential in the QC lab, say researchers who claim that a new intact protein analysis method overcomes challenges that have up to now limited adoption. Growing ...

Researchers have detailed PEPPI-MS, an experimental protocol combining high-resolution protein fractionation using SDS-polyacrylamide gel electrophoresis (SDS-PAGE) with the latest mass spectrometry ...

This Clinical Chemistry and Laboratory Medicine review examines a central challenge in precision medicine: whether medical ...

Chemical analysis is a critical need in our high-tech industrial world. Mass spectrometry, with its high sensitivity and high selectivity, occupies a pivotal role in the detection and quantitation of ...

Researchers have developed a method to evaluate the folding stability of a million proteins simultaneously. DNA libraries were used to generate protein -- DNA complexes that were treated with enzymes ...

The proteome is perhaps the most dynamic and valuable source of functional biological insight. Here, we introduce a novel single-molecule proteomic analysis approach that includes novel biochemistry ...