Weight-loss responses to GLP-1 obesity drugs, and risks of side effects, may be linked to genetic variants, according to a ...

Distinct GLP1R and GIPR variants correlated with nausea/vomiting risk, with a GIPR signal appearing tirzepatide-specific and showing markedly increased vomiting odds. New studies from 23andMe suggest ...

Developmental dysplasia of the hip (DDH) is a polygenetic disorder that increases the risk of hip osteoarthritis.

The study of genetic variation and growth traits in tree species is crucial for understanding the mechanisms that underpin forest productivity, resilience and adaptation. Recent advances in molecular ...

A large 23andMe-based GWAS found that common variants in GLP1R and GIPR help explain why some people lose more weight or ...

Researchers still do not have a comprehensive picture of the factors that influence gene expression in human cancers. Understanding gene expression in cancer is important because it can reveal how the ...

PerturbFate can systematically map how diverse disease-associated genetic variations reshape cells to understand complex diseases, like cancer.

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder that is thought to have a significant link to ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we evolved. But some of the most changeable regions of our DNA have been ...

Genetic variation in livestock is a critical area of research that underpins modern breeding practices and agricultural productivity. Differences in DNA sequences, including single nucleotide ...