The geometry of the zebrafish egg is shown to generate a gradient in cell size upon successive cell divisions. This gradient specifies stereotyped patterns of cell-cycle progression, zygotic genome ...

Chromocenters in mouse cells are membrane-less nuclear compartments representing typical heterochromatin stably maintained during cell cycle. We explore how histone H3 variants, replicative H3.1/2 or ...

Glycolysis is an ancient metabolic activity. It consists of a set of reactions that convert glucose into energy. This central process allows cells to grow, divide, and stay alive. It has accompanied ...

Life begins with a single fertilized cell that gradually transforms into a multicellular organism. This process requires precise coordination; otherwise, the embryo could develop serious complications ...

Researchers from the Kind Group have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization ...

We have identified the gene that, when activated, initiates the developmental programme that results in cells forming a human ...

An international team of experts in embryology and bioethics has published the first white paper on the use of embryonic ...

Most people have heard of stem cells. They are often described as "miracle" cells –ones that can grow into any other type of cell in our bodies, promising revolutionary medical treatments. However, ...

Scientists in the Brivanlou lab used light-inducible gene expression (yellow circle) and embryo models to demonstrate that, at the start of gastrulation, body-axis formation requires an interplay ...

Scientists found that embryonic skin cells “whisper” through faint mechanical tugs, using the same force-sensing proteins that make our ears ultrasensitive. By syncing these micro-movements, the cells ...

Left: staining for H3K27me3, which marks inactive DNA, on a nucleus of a wildtype embryo consisting of two cells Right: staining for H3K27me3, which marks inactive DNA, on a nucleus of an embryo ...

Most people have heard of stem cells. They are often described as “miracle” cells –ones that can grow into any other type of cell in our bodies, promising revolutionary medical treatments. However, ...