ctDNA test, which is an important aspect in liquid biopsy, offers a non-invasive alternative to tissue biopsies for cancer diagnosis and monitoring. Ultra-deep ctDNA sequencing enabling the detection ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

Despite advanced diagnostic tools, early detection of rare genetic conditions like Noonan syndrome (NS) remains challenging. We evaluated a deep learning model’s real-world performance in identifying ...

Next-generation sequencing is essential for microbiome research, as it enables comprehensive analysis of large datasets. Therefore, the robustness and accuracy of bioinformatic workflows for sequence ...

EV-302: Long-term subgroup analysis from the phase 3 global study of enfortumab vedotin in combination with pembrolizumab (EV+P) vs chemotherapy (chemo) in previously untreated locally advanced or ...

The deep sea is a unique "evolutionary engine," with one of the richest and most unexplored sources of genetic diversity on Earth, according to a major new study that assessed its potential to ...

Deep-sea researchers uncovered more than 500 million unique genes and a promising protein that could improve DNA sequencing ...