Nearly half of the patients with rheumatoid arthritis (RA) in sustained clinical and ultrasound remission still report unacceptable pain, with women experiencing higher pain levels than men. Patient ...

When pain strikes from multiple sources—such as a paper cut followed by contact with hot water—the experience can feel disproportionately intense. But is this agony merely additive, or does the brain ...

A breakthrough discovery reveals how the SLC45A4 gene fine-tunes polyamine transport in sensory neurons, reshaping our understanding of pain and opening new paths for targeted therapies. Study: ...

Pain has a protective role. A primary role of acute pain is to protect us from further harm. For example, a painful blister on your foot can motivate you to stop walking or to wear more comfortable ...

Chronic pain continues to be one of the most challenging health problems that exists. Sadly, the suffering from chronic pain often flummoxes the medical community and leads to people feeling ignored ...

When you stub your toe or bump your head, you know that rubbing the injury can lessen the ouch. But how? New research from the lab of Scott B. Hansen, Ph.D., shows how physical pressure on cells can ...

PTSD is often accompanied by chronic pain. It stems from the physiological and psychological impacts of trauma and stress. The link between post-traumatic stress disorder (PTSD) and chronic pain is ...