New research has identified a protein that could serve as both a biomarker and therapeutic target to weaken stem-like cancer ...

Chemotherapy kills cancer cells, but it also leaves behind something troubling: damaged cells that stop dividing yet refuse ...

A peptide that successfully targeted and killed metastatic cancer cells in mice may open the door to developing more ...

Senescent cells walk a tightrope, risking cell death with high levels of iron and other damaging agents, but compensating for this by overproducing a protective protein, GPX4, which staves off death.

Scientists have developed a way to turn the body's own immune cells into cancer-fighting agents—without removing them from ...

OCTOPOD-IP is being conducted to investigate intraperitoneal (IP) administration of THEO-260 in women with advanced platinum-resistant ovarian cancerRecruitment on track in OCTOPOD-IV, a Phase 1/2a ...

Medicinal chemists think a lot about minimizing off-target effects. But for this family of transcription factors, hitting ...

Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an unconventional approach to metastatic cancer. Rather than targeting cancer cells ...

Cancer treatment has long been haunted by the same problem: how do you strike dangerous cells without hitting healthy ones nearby? A team at the University of Geneva has built a drug-delivery system ...

This research opens up new avenues for better understanding the metabolic vulnerabilities of cancers,” Jourdain said, “and ...