Argonaute proteins facilitate guide oligonucleotide-mediated binding of nucleic acid targets to perform a wide range of functions in prokaryotes and eukaryotes. In eukaryotic RNA silencing pathways, ...
CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel ...
Genome-wide genetic screens for knockout using the CRISPR/Cas9 system have been immensely powerful in identifying genes that are essential for the viability of cancer cells 1,2. These fitness genes ...
In vivo delivery of targeted RNA acetylation system. The targeted RNA acetylation system was encoded in an AAV vector, commonly used in gene therapy, and delivered intravenously to adult mice, showing ...
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